This book provides a comprehensive foundation for the contemporary application of pharmacokinetics and pharmacodynamics. The second edition updates and strengthens existing chapters and adds new topics to address current needs including physiologically based pharmacokinetic modeling, pharmacogenomics and predicting drug-drug interactions. Reviews of the First Edition: I could recommend Rosenbaum's book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD that may fill a small niche in a well-served market. (British Toxicology Society Newsletter, 1 June 2012) In summary, I believe that this book is successful in what it sets out to do. For those readers who are interested in getting to grips with the basics of the time course of onset, offset and extent of drug effects then this is the book for you. I am certainly recommending this book for my graduate students. (British Journal of Clinical Pharmacology, 2011) Scientists working in pharmacokinetics and pharmacodynamics (PK and PD) study the behavior of drugs in the body. This includes how drugs are absorbed into the body, where they go, what they do, and how the body gets rid of them. Models can be applied to help understand these processes. The combined subject of PK/PD is an important component of the education of health professionals and research scientists involved with drugs. Updated with new chapters and topics, the new edition of Basic Pharmacokinetics and Pharmacodynamics